Error sending mail: ‘SMTP protocol returned a permanent error: 554 relay rejected for policy reasons’

Problem

A user attempts to send a new mail message from Lotus Notes® and the following error message appears, preventing the message from being sent:
Error: SMTP protocol returned a permanent error: 554 relay rejected for policy reasons.    
   
Solution

A setting in the user’s Location document was incorrectly set. On the Mail tab, “Send outgoing mail” was incorrectly set to “Directly to Internet.” After changing the field to “through Domino server” the problem was resolved. 

Sumber : www-10.lotus.com

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